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Treating Diabetic Nephropathy in Primary Care

Diabetic nephropathy has been categorized into two stages based on the degree of urinary albumin excretion (UAE): microalbuminuria and macroalbuminuria. Microalbuminuria is both a predictor of progression of nephropathy and an independent risk factor for cardiovascular disease (CVD), and evidence to date suggests that the risk for developing diabetic nephropathy and CVD begins when UAE values are still within the normoalbuminuric range. In addition, patients that do not receive effective treatment for diabetic nephropathy can experience renal failure, leading to end-stage renal disease (ESRD).


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